The application of the medication Superlimf in the peri-implant area after vestibuloplasty

Abstract

During dental implantation, it is necessary to achieve not only osseointegration of an implant, but also mucogingival integration in the suprastructure area. The solution of the optimization problem of regeneration processes in the peri-implant area after vestibuloplasty is aimed at finding immunomodulating agents for local application.
Materials and methods.
The study involved 32 patients aged 27 to 73 years with previously installed dental implants and with insufficient volume of the attached gum in the peri-implant area. Patients underwent vestibuloplasty using a donor free epithelial autograft obtained from one of the two segments of the hard palate. After vestibuloplasty, the patients of the main group (n=16) were treated with the medicaton Superlimf in the form of alginate plates, while the adhesive gum balm Asepta was used for the patients in the control group (n=16).
Results.
During the assessment of clinical parameters for photoprotocols, 4 photometric parameters were identified according to the degree of coating of the wound surface with fibrinous film. It was found that the minimum area from 0 to 25% was observed in 75% of patients in the main group and only in 19% of patients in the control group (p=0005). In the control group, the coverage area of the wound surface in the range of 25—50% was 69% of cases versus 19% in the main group (p=0.013). Large areas of fibrinous film coverage from 50% to 75% and within 75—100% in both groups were found in single quantities: the coverage area of 50—75% in one patient in the main group and one patient in the control group; the coverage area of 75—100% in one patient in the control group, and in No patients of the main group were observed (χ2=10.79, p=0.012). Cytological examination demonstrated the ratio of the activity of regenerative and inflammatory processes in the operated area of patients of the main and control groups. The predominance of regenerative processes was 69% in the main group versus 19% of cases in the control group (p=0.013). The equal severity of regenerative and inflammatory processes was observed in 19% of cases in the main group and in 50% of patients in the control group. The predominance of the inflammatory process in patients of the main group was observed in 13% of cases, while in patients of the control group in 31% of cases (χ2=8.13, p=0.017).
Conclusion.
The use of the medication Superlimf after vestibuloplasty indicates the dominance of regeneration processes over inflammation processes in the operated area. The medication Superlimf in the form of alginate plates for the oral cavity can be recommended in order to optimize the regeneration of peri-implant soft tissues after vestibuloplasty.