DOI:
10.37988/1811-153X_2023_3_115Oral virome: the beginning of the path (review)
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Abstract
The human oral virome is a part of the microbiome as a community of microorganisms inhabiting the oral cavity, includes eukaryotic viruses that persist in the human body and microbial viruses (bacteriophages). Virome performs the most important physiological functions to protect the human body from pathogens through the control of the microbiome composition, the impact on the formation of biofilms, immunomodulatory effects, plays a huge role in the human evolution as a whole, but often serves as a source of serious diseases. Among the eukaryotic viruses inhabiting the oral cavity, the leading role in the development of pathological conditions of this localization, in particular, periodontal diseases, belongs to herpesviruses (Epstein—Barr virus, cytomegalovirus), the etiopathogenetic significance of which is only partially deciphered and it remains to be clarified. In the fight against diseases of the oral cavity, the use of bacteriophages is promising, although the conditions and variants for their use need further study.Key words:
virome, microbiome, eukaryotic viruses, bacteriophages, herpesvirusesFor Citation
[1]
Balmasova I.P., Tsarev V.N., Gvetadze R.S., Mustafaev M.S., Tsareva T.V., Malova E.S., Arutyunov D.S., Timoshchenko M.V., Kharakh Ya.N., Arutyunov S.D. Oral virome: the beginning of the path (review). Clinical Dentistry (Russia). 2023; 26 (3): 115—124. DOI: 10.37988/1811-153X_2023_3_115
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Received
June 18, 2023
Accepted
August 20, 2023
Published on
September 24, 2023