DOI:

10.37988/1811-153X_2022_4_44

Comparative evaluation of the effect of topical and systemic dosage forms on oral microbiocenosis in difficult eruption of temporary teeth

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Authors

  • V.N. Tsarev 1, PhD in Medical Sciences, full professor of the Microbiology, virology, immunology department, director of the Medico-dental research Institute
    ORCID ID: 0000-0002-3311-0367
  • L.P. Kiselnikova 1, PhD in Medical Sciences, full professor of the Paediatric dentistry Department
    ORCID ID: 0000-0003-2095-9473
  • M.S. Podporin 1, PhD in Medical Sciences, researcher at the Molecular biology research Laboratory of the Medico-dental research Institute
    ORCID ID: 0000-0001-6785-0016
  • F.M. Balafendieva 1, postgraduate at the Paediatric dentistry Department
  • 1 Moscow State University of Medicine and Dentistry, 127473, Moscow, Russia

Abstract

Eruption of temporary teeth in children is accompanied by unpleasant pain sensations, development of edema, inflammation of the gums, changes in oral microbiocenosis. The purposes of the study is a clinical and microbiological assessment of the effectiveness of the use of various drugs for difficult teething, as well as a comparative assessment of the effect of these drugs on local and general symptoms of teething and oral microbiocenosis in children. >. Children with difficult teething (40 people each) aged from 5 months to 2 years were selected in 3 clinical groups. To assess the dynamics of the dental status and the state of oral microbiocenosis, clinical and microbiological (laboratory) research methods were performed for all the subjects. During 8 days children got treatment for managment of symptoms of teeth eruption: Dantinorm Baby (inside intake of oral solution), Calgel (locally on the gums), Viburgel (locally on the gums), and then a repeat study was performed. >. According to the results of the conducted studies and statistical data processing, it was found that the disappearance of local symptoms of difficult teething was more pronounced in the group of children in whose treatment the drug Dantinorm Baby was used (92% of cases). Against the background of the use of all drugs, the number of cariesogenic streptococci S. mutans decreased, and when using Dantinorm Baby — both S. mutans (from 95 to 80%) and A. naeslundii (from 10 to 0%) and some periodontopathogenic species (P. intermedia — from 10 to 3%). The effect of the drug Dantinorm Baby is accompanied by its normalizing effect on oral microbiocenosis.

Key words:

difficult eruption, oral microbiocenosis, cariesogenic streptococci, periodontopathogenic species

For Citation

[1]
Tsarev V.N., Kiselnikova L.P., Podporin M.S., Balafendieva F.M. Comparative evaluation of the effect of topical and systemic dosage forms on oral microbiocenosis in difficult eruption of temporary teeth. Clinical Dentistry (Russia).  2022; 25 (4): 44—49. DOI: 10.37988/1811-153X_2022_4_44

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Received

October 29, 2022

Accepted

December 6, 2022

Published on

December 21, 2022